Glial cells in (patho)physiology
نویسندگان
چکیده
منابع مشابه
Excitotoxicity in glial cells.
Excitotoxicity results from prolonged activation of glutamate receptors expressed by cells in the central nervous system (CNS). This cell death mechanism was first discovered in retinal ganglion cells and subsequently in brain neurons. In addition, it has been recently observed that CNS glial cells can also undergo excitotoxicity. Among them, oligodendrocytes are highly vulnerable to glutamate ...
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The nervous system is built from two broad categories of cells, neurones and glial cells. The glial cells outnumber the neurones and the two cell types occupy a comparable amount of space in nervous tissue. The main glial cell types are, in the central nervous system, astrocytes and oligodendrocytes and, in the peripheral nervous system, Schwann cells, enteric glial cells and satellite cells. I...
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a common pathological process that occurred after brain injury is gliosis. gliosis involves the activation of glial cells to proliferate and become hypertrophic to occupy the injured brain areas. in order to form a defense system against the invasion of micro-organisms and cytotoxins into surrounding tissue, glial cells including astrocytes and microglia undergo reactive response to injury. neu...
متن کاملPathophysiology of Schizophrenia Based on Impaired Glial-Neuronal Interactions
The model of impaired glial-neuronal interactions in schizophrenia is based on the core hypothesis that nonfunctional astrocyte receptors may cause an unconstrained synaptic information flux such that glia lose their modulatory function in tripartite synapses. This may lead to a generalization of information processing in the neuronal networks responsible for delusions and hallucinations on the...
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ژورنال
عنوان ژورنال: Journal of Neurochemistry
سال: 2012
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.2012.07664.x